EFFECTS OF ANAESTHETICS AND THEIR INTERACTIONS WITH NEUROMUSCULAR BLOCKING AGENTS IN CATS
نویسندگان
چکیده
منابع مشابه
Effects of anaesthetics and their interactions with neuromuscular blocking agents in cats.
In cats lightly anaesthetized with chloralose, ventilation with 75 per cent nitrous oxide did not affect arterial blood pressure, heart rate or the responses of gastrocnemius muscles to indirect stimulation; blockade by tubocurarine and gallamine was significantly enhanced but that by suxamethonium was almost unchanged. Ventilation with approximately 0.5 per cent halothane caused hypotension an...
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The interactions of four anaesthetic drugs (ketamine, propanidid, Althesin and methohexitone) with two neuromuscular blocking agents (suxamethonium and pancuronium) have been investigated. On the isolated rat phrenic nerve-diaphragm preparation, all the anaesthetic drugs examined potentiated suxamethonium more than they potentiated pancuronium. The anticholinesterase agent, ecothiopate, had no ...
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The potential changes In neuromuscular blockade after chronic (>24 h) administration of sub-paralytic doses of two newly introduced aminosteroidal muscle relaxants were investigated. Org-9426 (rocuronium) and Org-9487 were studied in the in vivo guinea pig gastrocnemius muscle-sciatic nerve preparation. The problems seen after prolonged administration of muscle relaxants are thought to ari...
متن کاملNeuromuscular Blocking Agents
• Neuromuscular blocking agents are used to improve conditions for tracheal intubation, to provide immobility during surgery, and to facilitate mechanical ventilation. • The main site of action of neuromuscular blocking agents (muscle relaxants) is on the nicotinic cholinergic receptor at the endplate of muscle. They also have effects at presynaptic receptors located on the nerve terminal. • Su...
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The effects on neuromuscular blockade by d-tubocurarine and succinylcholine of inhibition of prostaglandin biosynthesis by indomethacin and of intra-arterial administration of prostoglandins E2 and F2 alpha, before and after inhibition of prostoglandin biosynthesis, were evaluated in the cat sciatic-tibialis preparation. Non-specific inhibition of prostaglandin biosynthesis by indomethacin 3 mg...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1970
ISSN: 0007-0912
DOI: 10.1093/bja/42.10.826